Facile generation of hydroxyl radical by photolyis of pyrimido[5,4-g]pteridinetetrone N-oxides in aqueous solution. A new efficient DNA-photocleaving agent
Abstract
Photolyis of pyrimido[5,4-g]pteridinetetrone N-oxide 2 in water with UV–VIS light (>355 nm) provides a convenient and efficient method for the clean generation of hydroxyl radicals, which are useful as DNA-cleaving agents.