Concise enantiodivergent synthesis of eutypoxide B
Abstract
The first enantiodivergent synthesis of eutypoxide B 1, a metabolite of the fungus Eutypa lata, has been accomplished in a stereo- and regio-controlled manner by using the single chiral building block 3 as a chiral equivalent of (Z)-cyclohex-2,5-dien-1,4-diol 2.