Novel synthesis of substituted cis-bicyclo[3.3.0]octanes via palladium-catalysed cyclisation and subsequent Baeyer–Villiger ring cleavage
Abstract
The formal transformation of cyclopentadiene to cis-bicyclo[3.3.0]octanes via endo-5-vinyl-2-norbornene involving two different oxidation reactions, such as Pd-catalysed cyclisation and Baeyer–Villiger (BV) ring opening is described.