Molecular receptor design for the complexing of dibutylmalonic acid
Abstract
The synthesis and binding properties of compounds with the basic structure of 2-amino-10-(3-aminophenyl)-9-phenylphenanthrene 1 are described. The key steps were the formation of the tetrasubstituted alkene 9 and its photocyclization to a diphenylphenanthrene skeleton. The more rigid bilactam 2 and the bis-diethylaminophosphonate 3 are good receptors for binding malonic acid derivatives in chloroform, via four-point hydrogen-bonding interactions.