Palladium-catalysed alkynyl-dehydroxylation of polyfluorophenols
Abstract
Treatment of polyfluorophenyl perfluoroalkanesulfonates RfSO3C6F4X-p(1, X = F, Cl) with alkynes in the presence of Pd(PPh3)2Cl2 or Pd(PPh3)4 and Et3N in DMF gave polyfluorophenylalkynes in good to high yields. The same products were also prepared in a one-pot reaction from the corresponding perfluoroalkanesulfonyl fluoride and polyfluorophenol in comparable yields.