Reactions of 19-ethoxycarbonyl-19-demethylvincadifformine: synthesis of 19-ethoxycarbonyl-19-demethylapovincamine
Abstract
(±)-19-Ethoxycarbonyl-19-demethylapovincamine has been prepared by the oxidative rearrangement of (±)-19-ethoxycarbonyl-19-demethylvincadifformine. An attempt to prepare strem-peliopine by the reductive rearrangement of 19-ethoxycarbonyl-19-demethyl-1,2-dehydroaspidospermidine, obtained from the same starting material, was unsuccessful.