Issue 9, 1992

A chemoenzymatic synthesis of enantiomerically pure (R)- and (S)-2-methyldecan-1-ol

Abstract

(R)- and (S)-2-methyldecan-1-ol 3a has been prepared in >98% enantiomeric excess (ee) by transesterification with vinyl acetate in chloroform in the presence of Pseudomonas fluorescens lipase. Oxidation of the alcohol 3a affords nearly optically pure 2-methyldecanoic acid 3b

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1992, 1159-1161

A chemoenzymatic synthesis of enantiomerically pure (R)- and (S)-2-methyldecan-1-ol

P. Ferraboschi, P. Grisenti, A. Manzocchi and E. Santaniello, J. Chem. Soc., Perkin Trans. 1, 1992, 1159 DOI: 10.1039/P19920001159

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