Lipase from Candida cylindracea allows discrimination between the two connectively non-equivalent hydroxy groups in primary diols or their esters via acylation–hydrolysis, with high regioselectivity. The same technique is used to distinguish between hydroxy groups of different nature in phenolic compounds.
G. Pedrocchi-Fantoni and S. Servi, J. Chem. Soc., Perkin Trans. 1, 1992, 1029 DOI: 10.1039/P19920001029
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