Radical cyclization of some unsaturated carbohydrate-derived acetals
Abstract
Treatment of halogeno acetals derived from deoxy-D-hexenopyranosides of erythro and threo configuration with tributyltin hydride with a radical initiator gave fused pyranofuranosides. This allowed the completely stereo and regio-specific introduction of a functionalized carbon chain at the C-2 or C-3 position of some carbohydrate templates.