Issue 7, 1992

Beckmann rearrangements in bicyclo[2.2.1]heptan-2-one oximes

Abstract

Although Beckmann rearrangement of norcamphor oxime 1 was unsatisfactory, proceeding in poor yield to give a mixture of lactam products, rearrangement of the E/Z oxime 9, or the pure E-isomer 10, upon treatment with methanesulfonyl chloride and triethylamine, gave the lactam 12 in good yield.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1992, 831-837

Beckmann rearrangements in bicyclo[2.2.1]heptan-2-one oximes

P. A. Hunt, C. J. Moody, A. M. Z. Slawin, D. J. Williams, P. L. Myers and C. Smith, J. Chem. Soc., Perkin Trans. 1, 1992, 831 DOI: 10.1039/P19920000831

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