A new synthetic route to furofuranoid lignans via the intramolecular Mukaiyama reaction
Abstract
The sequence set out in Scheme 1 provides a short and expedient synthesis of a number of (±)-furofuranoid lignans, including styraxin 3(antitumour), aptosimon 5, asarinin 6, pluviatilol 7, ‘MEL’4(inhibitor of germination) and related compounds.