Issue 1, 1992
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Pennigritrem, a naturally-occurring penitrem A analogue with novel cyclisation in the diterpenoid moiety

Julia Penn,   Jeremy R. Biddle,   Peter G. Mantle,   John N. Bilton  and  Richard N. Sheppard  

Abstract

A prominent novel analogue of penitrem A has been resolved from the tremorgenic alkaloids of a strain of Penicillium nigricans and the structure, elucidated by NMR spectroscopy, shown to involve the terminal diterpenoid isoprene in a cyclisation which is unique amongst fungal indolediterpenoids. Consequent conformational changes in the biologically active moiety significantly reduced tremorgenicity.

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Article information

DOI
https://doi.org/10.1039/P19920000023
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1992, 23-26

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Pennigritrem, a naturally-occurring penitrem A analogue with novel cyclisation in the diterpenoid moiety

J. Penn, J. R. Biddle, P. G. Mantle, J. N. Bilton and R. N. Sheppard, J. Chem. Soc., Perkin Trans. 1, 1992, 23 DOI: 10.1039/P19920000023

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