Issue 15, 1992

Synthesis and X-ray crystal structure of 2-acetyl-9-azabicyclo[4.2.1]nonan-3-one. A conformationally locked s-cis analogue of anatoxin-a

Abstract

2-Acetyl-9-azabicyclo[4.2.1]nonan-3-one 2(‘hydroxyanatoxin-a’), which represents a conformationally locked variant of the s-cis conformer of the potent cholinergic agonist anatoxin-a, is synthesised and characterised; this molecule lacks both nicotinic and muscarinic potency.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 1087-1089

Synthesis and X-ray crystal structure of 2-acetyl-9-azabicyclo[4.2.1]nonan-3-one. A conformationally locked s-cis analogue of anatoxin-a

P. A. Brough, T. Gallagher, P. Thomas, S. Wonnacott, R. Baker, K. M. A. Malik and M. B. Hursthouse, J. Chem. Soc., Chem. Commun., 1992, 1087 DOI: 10.1039/C39920001087

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements