2-Chloromethyl-4-nitrophenyl α-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl α-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast α-glucosidase and is much superior in this respect to 2-chloromethylphenyl α-D-glucopyranoside.
J. C. Briggs, A. H. Haines and R. J. K. Taylor, J. Chem. Soc., Chem. Commun., 1992, 1039 DOI: 10.1039/C39920001039
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