Issue 12, 1992

A facile regioselective aromatic fluorination of N-aryl-N-hydroxyamides with diethylaminosulfur trifluoride (DAST)

Abstract

Treatment of N-aryl-N-hydroxyamides with diethylaminosulfur trifluoride (DAST) under conventional reaction conditions results in removal of the hydroxy function and introduction of a fluorine atom at the para position of the aromatic ring, in high yield.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1992, 921-922

A facile regioselective aromatic fluorination of N-aryl-N-hydroxyamides with diethylaminosulfur trifluoride (DAST)

Y. Kikugawa, K. Matsumoto, K. Mitsui and T. Sakamoto, J. Chem. Soc., Chem. Commun., 1992, 921 DOI: 10.1039/C39920000921

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