Issue 9, 1991

Biosynthetic origins of the polycyclic xanthone antibiotic, citreamicin

Abstract

The biosynthesis of citreamicin 1 has been studied by feeding 13C- and 18O-labelled precursors to Micromonospora citrea cultures. 13C-NMR spectroscopic analysis of the enriched products demonstrated a labelling pattern indicating that the antibiotic is derived from a polyketide which undergoes rearrangement by a mechanism unique for xanthone biosynthesis.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1991, 2215-2219

Biosynthetic origins of the polycyclic xanthone antibiotic, citreamicin

G. T. Carter, D. B. Borders, J. J. Goodman, J. Ashcroft, M. Greenstein, W. M. Maiese and C. J. Pearce, J. Chem. Soc., Perkin Trans. 1, 1991, 2215 DOI: 10.1039/P19910002215

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