Chemistry of 2-azabicyclo[2.2.1 ]heptan-3-one derivatives: role of the nitrogen atom in determining the stereochemistry of products isolated after formation of an incipient carbocation at C-6
Abstract
The nitrogen atom of the amide group is responsible for retention of stereochemistry for the products obtained when the alcohol 6 is allowed to react under Mitsunobu conditions and when 6 is treated with diethylaminosulphur trifluoride.