A facile chemoenzymatic route to enantiomerically pure oxiranes: building blocks for biologically active compounds
Abstract
The enantiomerically pure building blocks (R)-and (S)-1–4 were prepared both by enantioselective, enzymatic hydrolysis and by acyl transfer, and subsequently converted into the corresponding enantiomerically pure oxiranes (R)- and (S)-7 and 8.