Sequential addition of 2-potassio-2-nitropropane and oxygen to 4-arylidene-oxazol-5-ones: a new method for 2-aryl butenoic acid imides
Abstract
The regiospecific addition of 2-potassio-2-nitropropane to the 4-arylidene-oxazol-5-ones followed by oxygenation led to 2-arylbutenoic acid imides, the key intermediate for several pharmacodynamic compounds in high yields.