Reaction of the acetate (±)-8 with the acid (±)-2 using Candida cylindracea lipase or Lipase AY as catalyst gave mainly the (R,R)-diastereoisomer 4(91 ± 0.5%) with minimal amounts of the other diastereoisomers 3, 5 and 6(<5.5%).
P. W. Fowler, E. L. A. Macfarlane and S. M. Roberts, J. Chem. Soc., Chem. Commun., 1991, 453 DOI: 10.1039/C39910000453
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