Use of molecular sieves for promotion of diastereoselectivity in palladium-catalysed oxidative cyclisation. Reversal of diastereofacial selectivity
Abstract
Molecular sieves have a decisive influence on the oxidative cyclisation of cis-1,2-divinylcyclohexane, resulting in enhanced diastereoselectivity (17–62%) as well as, occasionally, in opposite absolute configuration of the newly created chiral centres.