The reaction of ketone alkylhydrazones with phosphorus trichloride and methyl acetoacetate: a mild new route to 2-alkenylpyrazol-3(2H)-one derivatives

Abstract

The title compounds have been synthesized by the one-pot reaction at room temperature of ketone alkylhydrazones, PCl₃ and methyl acetoacetate; a single crystal X-ray structure determination of the minor isomer of one derivative permitted the assignment of its structure and showed the Z-configuration of the alkenyl group.