Issue 5, 1991

Structural studies on bio-active molecules. Part 17. Crystal structure of 9-(2′-phosphonomethoxyethyl)adenine (PMEA)

Abstract

The crystal structure of the antiviral agent PMEA 1 has been determined to R= 0.032 and reveals a zwitterion whose side chain emerges in-plane from the adenine ring; the conformation is compared with that of crystal structures of acyclic nucleoside analogues and AMP 2.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1991, 1348-1349

Structural studies on bio-active molecules. Part 17. Crystal structure of 9-(2′-phosphonomethoxyethyl)adenine (PMEA)

C. H. Schwalbe, W. Thomson and S. Freeman, J. Chem. Soc., Perkin Trans. 1, 1991, 1348 DOI: 10.1039/P19910001348

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