Studies on synthesis of plant growth hormone steroids. Part 16. Stereoselective synthesis of 26,27-dinorbrassinolide
Abstract
26,27-Dinorbrassinolide, having a (20S,22R,23R)-22,23-dihydroxy-unit side-chain, was stereo-selectively synthesized from hyodeoxycholic acid via successive lactonization, oxidation, and reduction of the key intermediate (Z)-(7).