Asymmetric Diels–Alder reaction with use of (S)-5-(trityloxymetyl)pyrrolidin-2-one as a chiral auxiliary
Abstract
(S)-5-(Trityloxymethyl)pyrrolidin-2-one (1) is an efficient and recyclable chiral auxiliary in the asymmetric Diels–Alder reaction of the imide (2) with dienes, affording cycloadducts (3) with excellent diastereofacial selectivity.
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