The successive reaction of diallyl amines 1 with several alkyllithium reagents and diethyl carbonate leads, after hydrolysis, to the corresponding pyrrolizidine derivatives 3 in a one-pot process; the reaction of intermediates 2 with carbon dioxide affords (Z)-amino acids 8, (E)-amino esters 9 or N-substituted butyrolactams 10.
J. Barluenga, F. Foubelo, R. González, F. J. Fañanás and M. Yus, J. Chem. Soc., Chem. Commun., 1990, 1521 DOI: 10.1039/C39900001521
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