The total synthesis of (+)-norpatchoulenol: trapping of a non-enolizable 1,3-diketone intermediate with a Wittig reagent
Abstract
A short total synthesis of (+)-norpatchoulenol (1) has been accomplished from (+)icamphor-10-sulphonic acid (2) involving, as a key step, the trapping of a non-enolizable 1,3-diketone intermediate with a Wittig reagent.