Theoretical prediction of the stereochemistry and regiochemistry in anionic addition to phospha-ethyne
Abstract
The regiochemistry of anionic addition to phospha-ethyne is shown, using MO calculations, to be dependent on the nature of the nucleophile, the hydride ion leading to initial C-attack whereas the fluoride ion prefers P-addition; the latter is predicted to be stereospecific irrespective of the nucleophilic agent.