Optically active diazoketones derived from N-protected amino acids and (S)-2-chloropropionic acid have been used as homochiral group transfer reagents in the synthesis of various optically active α-functionalised ketones and related compounds.
J. C. Collins, B. M. Dilworth, N. T. Garvey, M. Kennedy, M. A. McKervey and M. B. O'Sullivan, J. Chem. Soc., Chem. Commun., 1990, 362 DOI: 10.1039/C39900000362
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