Facile synthesis of the 4-azatricyclo[2.2.1.02,6]heptane system
Abstract
1-Methoxycarbonyl-4-azatricyclo[2.2.1.02.6]heptane has been prepared by an efficient carbonium ion mediated rearrangement and shown to have a relatively low pKa; the crystal structure of the hydrochloride salt has been determined.