Issue 12, 1989

Preparation and conformational analysis of vancomycin hexapeptide and aglucovancomycin hexapeptide

Abstract

The preparations of the hexapeptides (3) and (6) derived from the antibiotic vancomycin (1), are described. The conformation of the N-terminal regions of (3) and (6) are discussed and compared to previous observations made on vancomycin. The hexapeptides lack any significant binding capability relative to vancomycin, and the reasons for this are discussed.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1989, 2335-2339

Preparation and conformational analysis of vancomycin hexapeptide and aglucovancomycin hexapeptide

P. M. Booth and D. H. Williams, J. Chem. Soc., Perkin Trans. 1, 1989, 2335 DOI: 10.1039/P19890002335

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