Synthesis of albidin (6-methoxy-3-methylisobenzofuran-4,5-dione) and (±)-curvulol [(±)-1,3-dihydro-6-methoxy-3-methylisobenzofuran-4,5-diol]
Abstract
The title compounds have been synthesised by a sequence involving as the key step the cyclization of the radical derived from the reaction of tributylstannane with 3,4-diacetoxy-2-bromo-5-methoxybenzyl vinyl ether.