The stereoselective introduction of a hydroxy group into the 2,8-dioxabicyclo[3.2.1]octan-3-one system
Abstract
The silyl lactone enol ether (2) provides a means for the stereospecific introduction of a hydroxy group at the 4-position of the 2,8-dioxabicyclo[3.2.1]octan-3-one system; the hydroxy group can also be inverted by treatment with base.