A rapid method for the determination of chlorpheniramine maleate in tablets using second-derivative absorption spectrophotometry is described. The method has the advantage of requiring simple sample preparation and having accuracy comparable to the official acid-alkaline solvent extraction procedure. Results of recovery tests were close to 100%.
C. Leung and C. Law, Analyst, 1989, 114, 241 DOI: 10.1039/AN9891400241
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