A mild method for the conversion of 1,3-glycols into unsaturated alcohols
Abstract
Some transformations of 1,3-glycols utilizing dimethylformamide dimethyl acetal have been examined with the diterpenoids aphidicolin and foliol and some steroids as substrates. Axial alcohols with a suitably disposed trans hydrogen atom undergo an elimination reaction to give the formate of an unsaturated alcohol via the quaternary salt of the cyclic formamido acetal.