Palladium-catalysed addition of chiral nucleophiles to non-conjugated dienes: enantioselective oxidative cyclization of cis-1,2-divinylcyclohexane
Abstract
Carboxylic acids react readily with cis-1,2-divinylcyclohexane; in the case of chiral acids, modest, but significant asymmetric inductions are observed during the palladium catalysed oxidation reaction.