The stereospecific synthesis of the novel spirocyclic unit (7), and its use in the construction by solid phase methods, of a conformationally locked analogue of the immunodominant nonapeptide (1) is described.
M. G. Hinds, N. G. J. Richards and J. A. Robinson, J. Chem. Soc., Chem. Commun., 1988, 1447 DOI: 10.1039/C39880001447
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