A series of novel 32-functionalised lanost-7-en-3-ols (1)–(7) has been synthesised; these compounds are all powerful inhibitors of lanosterol 14α-methyl demethylase, an important enzyme in cholesterol biosynthesis.
L. L. Frye and C. H. Robinson, J. Chem. Soc., Chem. Commun., 1988, 129 DOI: 10.1039/C39880000129
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