Issue 0, 1987

N-monomethylation of primary amines via intermediate benzothiazol-2(3H)-imines

Abstract

Aliphatic and aromatic amines are converted by successive treatment with (i) 3-methyl-2-methylthiobenzothiazolium iodide, (ii) methyl iodide or toluene-p-sulphonate, and (iii) butylamine, in high yield under mild conditions into their mono-N-methyl derivatives.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1987, 2539-2541

N-monomethylation of primary amines via intermediate benzothiazol-2(3H)-imines

A. R. Katritzky, M. Drewniak and J. M. Aurrecoechea, J. Chem. Soc., Perkin Trans. 1, 1987, 2539 DOI: 10.1039/P19870002539

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