Aspidosperma alkaloids. Conversion of tabersonine into vindoline
Abstract
An efficient synthesis of vindoline, the indoline portion of the clinically useful antitumour agent vinblastine, starting from tabersonine is described.
An efficient synthesis of vindoline, the indoline portion of the clinically useful antitumour agent vinblastine, starting from tabersonine is described.
B. Danieli, G. Lesma, G. Palmisano and R. Riva, J. Chem. Soc., Perkin Trans. 1, 1987, 155 DOI: 10.1039/P19870000155
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