Novel long-range 1H and 13C n.m.r. isotope effects transmitted via hydrogen bonds in a macrolide antibiotic: bafilomycin A1
Abstract
Novel, long-range (up to 12 bonds) isotope effects transmitted via hydrogen bonds were observed in the 1H and 13C n.m.r. spectra of bafilomycin A1(1) upon partial deuteriation of the exchangeable protons.