Koji Yamamoto, Hiroyuki Ando and Hiroaki Chikamatsu
J. Chem. Soc., Chem. Commun., 1987, 334-335
DOI:
10.1039/C39870000334,
Paper
An efficient microbial resolution of 1,3-diphenylpropane-1,3-diol (4) has been achieved by exposing the corresponding diacetate to Trichoderma viride; a reductive cleavage of chiral acetals (6) derived from (4) with hydride reagent (Br2AlH, Cl2AlH) affords optically active alcohols (8) of high enantiomeric purities.
