The n–π* optical activity of a ketone predicted to be optically inactive by the octant and quadrant rules: (1R,5R)-dimethyladamantan-2-one
Abstract
The title compound, which has each of its methyl groups lying in a quadrant or octant rule symmetry place, exhibits a weak positive n–π* circular dichroism Cotton effect, Δε292max.=+0.009.