Issue 0, 1986

Cyclobutarenes. Part 2. Azaquinomethanes as reactive intermediates: synthesis of cyclobuta[b]pyridine and cyclobuta[b]pyrazine derivatives

Abstract

Cyclisation of 2,3-bis(dibromomethyl)pyridine (1) and 2,3-bis(dibromomethyl)pyrazine (3) with sodium iodide gives the dibromodihydrocyclobutarenes (10) and (13). The intermediate quinomethanes (6) and (7), together with the pyrimidine and 1,2,4-triazine analogues (8) and (9), are readily trapped via cycloaddition reactions.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1986, 1495-1498

Cyclobutarenes. Part 2. Azaquinomethanes as reactive intermediates: synthesis of cyclobuta[b]pyridine and cyclobuta[b]pyrazine derivatives

M. K. Shepherd, J. Chem. Soc., Perkin Trans. 1, 1986, 1495 DOI: 10.1039/P19860001495

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