Total synthesis of a (±)-secologanin aglucone and (±)-elenolide
Abstract
The rearranged (E)-aglucone of secologanin (3) and the related monoterpene elenolide (4) have been prepared via substituted hydroxycyclopentenones in a short reaction sequence involving chemoselective demethoxy-carbonylation and regioselective allylic bromination.