Issue 16, 1986

Penicillin biosynthesis: structure–reactivity profile of allenic substrates for isopenicillin N synthetase

Abstract

Two allene-containing tripeptides (1b) and (1c) have been prepared and evaluated as substrates for isopenicillin N synthetase; the formation of penam, cepham, and dienyl products is consistent with the operation of desaturative ring closures.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 1280-1281

Penicillin biosynthesis: structure–reactivity profile of allenic substrates for isopenicillin N synthetase

J. E. Baldwin, R. M. Adlington, A. Basak and H. Ting, J. Chem. Soc., Chem. Commun., 1986, 1280 DOI: 10.1039/C39860001280

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