Synthesis of optically active (–)-trachelanthamidine from L-prolinol
Abstract
(–)-Trachelanthamidine was synthesised in an optically active form from L-prolinol, using olefin cyclisation initiated by an α-thiocarbocation as the key step.
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(–)-Trachelanthamidine was synthesised in an optically active form from L-prolinol, using olefin cyclisation initiated by an α-thiocarbocation as the key step.
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H. Ishibashi, H. Ozeki and M. Ikeda, J. Chem. Soc., Chem. Commun., 1986, 654 DOI: 10.1039/C39860000654
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