Total synthesis of hydrocinchonidine and hydrochinchonine from an indole derivatives via oxidation with singlet oxygen
Abstract
Hydrocinchotoxine (9), which has been converted into hydrocinchonidine (10) and hydrocinchonine (11), was synthesised via photo-oxygenation of the indole derivative (7) followed by treatment with dimethyl sulphide and dilute acetic acid.