The formation and double decomposition of pyridoxal isonicotinoylhydrazone dimethiodide mediated by iron(II) salts
Abstract
Iron(II) ions are shown to induce a hitherto unknown nitrogen-centred metathesis (‘hydrazine metathesis’) of pyridoxal isonicotinoylhydrazone dimethiodide (1) into the symmetrical hydrazine derivatives pyridoxal azine dimethiodide (7) and dimethiodide of bis-isonicotinoyl hydrazide (8) together with isonicotinoylamide methiodide (9) in a ratio 2 : 1 : 1, respectively.