An asymmetric synthesis of chiral nifedipine analogues
Abstract
The addition of aryl-lithium reagents to chiral pyridyl-dihydro-oxazoles gave (S)-4-aryl-1,4-dihydropyridines in 80–90% enantiomeric excess.
The addition of aryl-lithium reagents to chiral pyridyl-dihydro-oxazoles gave (S)-4-aryl-1,4-dihydropyridines in 80–90% enantiomeric excess.
A. I. Meyers and T. Oppenlaender, J. Chem. Soc., Chem. Commun., 1986, 920 DOI: 10.1039/C39860000920
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